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From "The Engineer", 2 April 2004
Plugging the gap
The UK is ahead of the game in what promises
to be one of the most exciting areas of applied technology in the
coming decade: the exploitation of TeraHertz imaging. For once Europe
in general and the UK in particular rather than the US or Japan
are setting the pace in what could turn into a huge new international
market with major implications for society and medicine. Advances
in physics and laser technology are unlocking the secrets of the
TeraHertz (THz) gap, described as the 'final frontier' of the radio
and light spectrum (see ‘The TeraHertz gap’ below).
Rather like nanotechnology, but without most
of the hype or any of the science fiction scaremongering, THz imaging
has the potential to enable significant technical advances in many
areas. These range from early detection of skin cancer and screening
for hidden explosives to a multitude of less high-profile but equally
revolutionary applications in industrial processes.
The two key pillars of a strong position in any
new technology are a healthy academic research base and an active
programme of commercialisation. Happily for the UK, things are currently
looking good on both counts. A significant chunk of the research
impetus will come from the Centre for TeraHertz Photonics at Leeds
University. Currently nearing completion, the centre will combine
the established expertise and resources of teams at Leeds and Cambridge
University into Europe's biggest THz research facility.
On the commercial front the UK boasts the world's
only company building actual products based on THz technology. Cambridge-based
TeraView is developing THz systems for a range of applications in
the industrial, medical and security sectors (see 'Commercial Possibilities
for THz' below). The company was one of only a handful of European
businesses recently to be named as pioneers of potentially world-changing
technology by the World Economic Forum.
So what is the immediate future for THz in the
UK? In Leeds Prof Giles Davies is supervising the final few months
of work that will bring some of the world's best THz expertise under
one roof in Yorkshire. Formerly part of Cambridge's pioneering THz
team, Davies and his colleagues will carry out research into sources,
detectors and applications of THz radiation. Davies said the potential
applications of THz are extensive, although he stressed the need
for caution at what is still a relatively early stage for much of
the research. Even so, he has every reason to be excited about the
new centre. As well as its size, the facility will have the advantage
of the considerable expertise and experience built up over the years
in Leeds itself and Cambridge. The two major THz projects mounted
by the EU have both been led by UK research teams. There are Teravision,
which investigated the use of THz in medicine, and Wanted, a wireless
networking initiative. A third may follow soon. 'We're doing phenomenally
well and are certainly very much up with the pack. The reason we're
leading these things is that we have the credibility, not just running
the programmes themselves but in the science behind the programmes,'
said Davies.
He and his colleagues will spend the next few
years exploring numerous potential applications for THz. These include
combustion and flame analysis. 'We will be looking at whether THz
radiation is capable of investigating the by-products of flames,'
said Davies. THz could be useful in specialised fields such as the
grain industry. The detection of moisture content and the location
of water in a batch of grain would be a valuable tool in the milling
process, said Davies. The technology may also have medical applications
beyond detection of skin cancer. It could, for example, be used
to look through bandages to assess the status of a healing wound.
This would avoid having to remove a dressing if the healing process
is proceeding well.
According to Davies, THz could also become a
valuable addition to the panoply of communications technologies.
'As far as communications is concerned you are unlikely to be able
to send a THz signal around the world,' he said. 'But it is possible
to imagine a local area THz network, perhaps in an office or factory.'
The properties of THz would make it suitable for such networks on
several counts, said Davies, not least containing the signal within
the four walls of the building. 'You would have the advantages of
the broad bandwidth, but if any of your industrial competitors was
standing outside the window they would not be able to access it
because THz is absorbed so heavily.'
Other work underway around the world includes
the investigation of THz as a means of detecting microscopic flaws
in steel. Davies said German researchers were using THz to look
at the surface of steel as it left the production process, using
it to spot indentations and impurities that remain invisible under
other inspection processes. Other specialist inspection activity
includes New York-based research to see whether THz can be used
to examine the tiles on the Space Shuttle. Defects on the tiles
on the outside of the shuttle were identified as a possible cause
of the Columbia disaster, and the US researchers hope THz could
detect problems on future flights.
Research into skin cancer detection will form
part of Leeds' investigations, but Davies is anxious not to stoke
expectations too early. 'I know what everyone wants to hear is that
we are going to use this to detect and cure skin cancer. But we're
not there yet, and won't be there for a number of years.'
With regard to security, the area that has brought
THz to a wider public's attention via the pages of the national
press, Davies is especially cautious. The possibility of THz being
used to screen people and baggage for hidden weapons and explosives
has struck a chord with an increasingly security-obsessed global
media. 'There have been some recent articles that haven't perhaps
been quite as rigorous as they could have been. It certainly is
on the table, because security has obviously been a very important
area particularly in the past few years.' Davies does have funding
specifically to explore these areas. 'We are going to be looking
at things like explosives to see whether we can use THz radiation
to locate them, to maybe see whether they are concealed in somebody's
clothing. But I really can't say any more until we have done the
research, and that's not going to be for another three years.'
Industrial process applications could, according
to Davies, emerge from among the plethora of research initiatives
to be early examples of working THz systems. 'There is a whole range
of things that people are trying. The truth is nobody currently
knows what the killer application is going to be. It would be great
to say that we are going to cure cancer doing this. On the other
hand, it could end up looking at something on a conveyor belt in
a factory, which could still be a multimillion-pound industry.'
Davies's contemporaries at the THz commercial
sharp end will certainly hope he is right. TeraView is very much
a pioneering venture, not just in THz technology but delivering
working commercial products. Unsurprisingly, the company is less
cautious than Davies over proclaiming THz as a technology that is
very much of the here and now. Its slick website is packed with
examples of why medical screening, security and industrial processes
could all benefit from the exploitation of the THz gap.
One of TeraView's key advantages is its status
as a first mover in commercialising the technology. Mick Withers,
the company's chief engineer, said this also brings its own special
challenges. 'We have to be especially diligent in producing our
products because nobody else has done the groundwork for us.' Like
its colleagues in academic research, TeraView is looking at the
plethora of potential uses for THz systems and trying to assess
their merits. As a commercial venture it has to pace itself and
be led to a certain extent by its various potential markets. In
this respect TeraView has been canny in its development programme,
creating a common platform that can be adapted relatively easily
to the needs of various applications and industries.
'We have fundamental components that can be used
in four completely different markets,' said Withers. Although the
core technology is the same, the user interface is unique to the
demands of the particular application. 'Customers in each sector
would think that they were completely different products,' added
Withers.
Although TeraView is developing products suitable
for each of its core areas - medical, security, pharmaceutical and
non-destructive testing - the rate of progress towards full-scale
commercialisation will inevitably vary. Medical applications, for
example, have more hurdles to jump in terms of gaining regulatory
approval. The pharmaceutical industry, however, is particularly
interested in THz's potential as an aid to drug discovery, formulation
and manufacturing. 'The pharmaceutical industry is quite happy to
put its money where its mouth is. It is used to the R&D phase
of technology.'
Happily for TeraView, a string of heavyweight
investors have also been prepared to put their cash behind the potential
of THz. TTP Ventures, an investor specialising in early-stage technologies,
helped spin TeraView out of Toshiba's Cambridge Research Laboratory
and has been a staunch supporter of the company ever since. David
Connell, the investment firm's chairman, said TeraView's rapid progress
in THz had made it 'the leading company in the field without a shadow
of a doubt. It is a firm with the potential to become a very serious
business.' In the wider context Connell said the UK was 'in as good
a position as it possibly could be' in terms of THz development.
'But the big issue is to ensure it remains at the front of the pack,'
said Connell. He claimed that the government had 'a key role to
play' in this respect. 'In certain sectors the customers and the
big specifiers are from the government, for security applications,
for example,' said Connell, who added that the support and involvement
of government agencies would be a major boost to the emergence of
the technology. 'Fortunately it looks as though that is happening.'
Through grants to academics and support for commercial
programmes, the police and military are already showing they mean
business when it comes to THz. The medical sector, ever cautious
when it comes to new technologies, will surely follow. And the industrial
sector has never been known to ignore a technology with the potential
to boost productivity and efficiency. If the roll-out of THz gathers
the momentum that many predict, the UK has a golden opportunity
to reap the rewards.
The TeraHertz gap
The TeraHertz gap, which lies between 100GHz
and 10THz, is the last unexplored part of the electromagnetic spectrum,
nestling between the microwave and infrared regions. While devices
such as mobile phones operate quite happily on one side and TV remote
controllers on the other, the THz gap has proved the toughest nut
for scientists to crack when it comes to developing electronic systems
that are able to generate and detect its radiation.
That is changing, thanks to a new generation
of ultra-fast pulsed lasers that can generate broad bandwidth THz
light. Early versions of these devices tended to be complex, bulky
and expensive. So academic and commercial research will concentrate
on increasing their performance and reducing their size and cost.
The reason for the excitement over THz is the unique properties
displayed by radiation in the gap. At THz frequencies common materials
such as living tissue and plastic become semi-transparent, yielding
a 3D image when targeted by a THz pulse that sweeps across its surface.
But THz's uses go well beyond visual inspection.
It can reveal the unique THz signatures of different types of substances,
allowing users to perform chemical and structural analysis of the
objects they are scanning. Because THz is heavily absorbed by water,
most of its medical applications are likely to be at or near the
body's surface, hence its early application to skin or teeth. With
dry substances THz can penetrate deeper, opening the way for scanning
of objects such as suitcases at airports.
Commercial Possibilities for THz
TeraView has grown rapidly since it was spun
out from Toshiba Research Europe's laboratory in 2001, following
almost a decade of work on source and detector technology relating
to THz radiation. Its intention was to bring products to market
quickly, and it laid down its marker with a succession of commercial
firsts. These included using THz to create images of cancer and
tooth decay, producing a portable THz imager and designing a hand-held
probe that can be used with THz.
TeraView has honed in on what it believes are
significant opportunities for THz in four distinct sectors. Security
screening has grabbed most of the headlines since September 11 propelled
the issue to the top of the global news agenda. THz radiation is
particularly good at penetrating clothes and revealing the type
of non-metallic objects that X-ray screening would miss during security
checks at airports. The technology's ability to carry out analysis
of a substance's chemical composition has also proved highly topical,
raising the possibility of THz scanners being used to screen incoming
mail for terrorist threats such as viruses like anthrax and biochemicals.
TeraView has also talked about applying THz to landmine detection.
On the medical front the potential for THz to
sit alongside other scanning technologies such as X-ray and MRI
has been recognised since the earliest days of research in the field.
TeraView has carried out trials with clinicians and patients, and
although the commercialisation path in the medical sector is long
and winding the opportunities are considerable. Because it is non-ionising,
THz radiation is safe for medical use and can provide detailed analysis
of soft tissue to detect the presence of tumours and other diseases.
It has also shown advantages over X-rays for early detection of
tooth decay.
The pharmaceutical industry may be among the
first to benefit from the application of THz. Its ability to analyse
chemical composition in detail opens the way for new tools in the
development and production of drugs. For example, TeraView has developed
techniques to assess the chemical stability of drugs in the purification
process prior to preparing them for patients.
Non-destructive testing is TeraView's fourth
major area of commercial focus. Terahertz pulsed imaging (TPI) techniques
developed by the company can be used in industrial applications
such as checking the interconnect structures inside semiconductors.

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